Matt Chapman homered twice and knocked in five runs Friday night while Kyle Harrison pitched six effective innings as the San Francisco Giants stopped the host San Diego Padres 8-3.

Harrison (1-0) allowed six hits and two runs, walking none and fanning five as he handed Bob Melvin his first win as San Francisco manager. Melvin was the Padres’ manager the last two years, taking them to the National League Championship Series in 2022.

Chapman belted a two-run shot off Joe Musgrove (0-1) to center field in the first, then capped the scoring in the ninth by blasting another two-run homer off Pedro Avila. The shot landed on the third level of the Western Metal Supply building beyond the left field wall.

Musgrove endured his second straight subpar outing, permitting eight hits and four runs over 5 2/3 innings with one walk and three strikeouts. He lasted only 2 2/3 innings on March 21 in a 15-11 win over the Los Angeles Dodgers in Seoul, South Korea, yielding seven hits and five runs.

Fernando Tatis Jr. cracked two solo homers and Manny Machado also clubbed a solo shot for San Diego, which was coming off a 6-4 win in its home opener on Thursday.

The Giants collected 13 hits in this one against four Padres pitchers, with Chapman leading the way with three. After his first-inning homer, San Francisco touched Musgrove for a third run in the inning via Thairo Estrada’s line-drive single to right that scored Wilmer Flores.

Jung Hoo Lee upped San Francisco’s advantage to 4-0 in the fourth with an RBI single that scored Patrick Bailey. Machado got the Padres on the board in their half of the fourth with his second homer.

Tatis unloaded his first homer in the sixth, reaching the second deck in left field, to slice the deficit to 4-2. The Giants made it 6-2 in the seventh on Chapman’s RBI double and Flores’ run-scoring single, both with two outs.

Tatis lined his second homer of the game in the bottom of the eighth.

–Field Level Media